The adipokine chemerin augments vascular reactivity to contractile stimuli via activation of the MEK-ERK1/2 pathway
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چکیده
منابع مشابه
Endothelium-Dependent Attenuating Effect of Trigonella foenum-graecum on the Contractile Vascular Reactivity of Diabetic Rats
The present study was undertaken to determine whether two-month treatment of streptozotocin (STZ)-diabetic rats with aqueous leaf extract of Trigonella foenum-graecum (TFG 200 mg/kg i.p.) could improve thoracic aortic responsiveness and to evaluate its endothelium dependency. For this purpose, vascular responses to KCl and noradrenaline (NA) were measured. Diabetic state significantly increased...
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15 صفحه اولThe Adipokine Chemerin Induces Apoptosis in Cardiomyocytes.
BACKGROUND The adipokine chemerin has been associated with cardiovascular disease. We investigated the effects of chemerin on viability and intracellular signalling in murine cardiomyocytes, and the effects of insulin and TNF-α on cardiomyocyte chemerin production. METHODS Hoechst dye vital staining and cell cycle analysis were used to analyse the viability of murine cardiac cells in culture....
متن کاملendothelium-dependent attenuating effect of trigonella foenum-graecum on the contractile vascular reactivity of diabetic rats
the present study was undertaken to determine whether two-month treatment of streptozotocin (stz)-diabetic rats with aqueous leaf extract of trigonella foenum-graecum (tfg 200 mg/kg i.p.) could improve thoracic aortic responsiveness and to evaluate its endothelium dependency. for this purpose, vascular responses to kcl and noradrenaline (na) were measured. diabetic state significantly increased...
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ژورنال
عنوان ژورنال: Life Sciences
سال: 2012
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2012.04.013